From the press release:
"First and foremost, the UV-5X3 was built by adding filtering and support for the 220MHz Amateur band. The original UV-5R was a 4-watt dual-band radio; while the UV-5X3 can now output 5-watts on VHF and 4-watts on both 1.25M and UHF. The UV-5X3 focused specifically on the amateur band frequencies of the 1.25M band during design. The UV-5X3 supports: 65-108MHz (RX only - FM Radio), 130-179.99MHz (RX/TX), 222-225.99MHz (RX/TX), and 400-520.99MHz (RX/TX)"The announcement also talks about simplified scanning, the option to sync the display (channel name and frequency), CHIRP as the programming software, and more.